Ramachandran Vijayan

Conformational Analysis of the DFG-Out Kinase Motif and Biochemical Profiling of Structurally Validated Type II Inhibitors

Ramachandran Vijayan, Peng He, Vivek Modi et al. · Journal of Medicinal Chemistry · 2014 · 230 citations · Full text

Drug Target, Kinase Inhibitors, Molecular Biology +18

Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening

Joseph D. Bauman, Disha Patel, Chhaya Dharia et al. · Journal of Medicinal Chemistry · 2013 · 90 citations · Full text

Structural Bioinformatics, Molecular Biology, Nucleic Acid Amplification Test +17

Antibiofilm effect of Nocardiopsis sp. GRG 1 (KT235640) compound against biofilm forming Gram negative bacteria on UTIs

Govindan Rajivgandhi, Ramachandran Vijayan, Muthuchamy Maruthupandy et al. · Microbial Pathogenesis · 2018 · 85 citations

Biofilms, Gram-negative Bacteriology, Antimicrobial Susceptibility +12

Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors

Joseph D. Bauman, Disha Patel, Steven F. Baker et al. · ACS Chemical Biology · 2013 · 84 citations · Full text

Structural Bioinformatics, Biomolecular Structure Prediction, Molecular Biology +18

Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease

Nanjie Deng, Stefano Forli, Peng He et al. · The Journal of Physical Chemistry B · 2014 · 75 citations

Free Energy, Immunology, Molecular Biology +23