Bruce E. Clurman

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Bin Zhang, Chris Gaiteri, Liviu‐Gabriel Bodea et al. · Cell · 2013 · 1.8K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

Markus Welcker, Amir Orian, Jianping Jin et al. · Proceedings of the National Academy of Sciences · 2004 · 949 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Cyclin E-CDK2 is a regulator of p27Kip1.

Robert J. Sheaff, Mark Groudine, Michael D. Gordon et al. · Genes & Development · 1997 · 927 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

<i>FBW7</i> mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

Jennifer O’Neil, Jonathan Grim, Peter R. Strack et al. · The Journal of Experimental Medicine · 2007 · 662 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation.

Bruce E. Clurman, Robert J. Sheaff, Kenneth S. Thress et al. · Genes & Development · 1996 · 493 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17