Gregory S. Parker

Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs

Amy L. Firth, Tushar Menon, Gregory S. Parker et al. · Cell Reports · 2015 · 325 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Structure-based Design of Pyridone–Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition

Siegfried Reich, Paul A. Sprengeler, Gary G. Chiang et al. · Journal of Medicinal Chemistry · 2018 · 177 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 Inhibitor, Is Efficacious in Preclinical Models of Diffuse Large B-Cell Lymphoma (DLBCL)

Kevin R. Webster, Vikas Goel, Ivy N. Hung et al. · Blood · 2015 · 26 citations

Medicine, Oncology, Pharmacology +6

Discovery of Monovalent Direct Degraders of BRD4 that Act via the Recruitment of DCAF11

Gregory S. Parker, Julia I. Toth, Sarah Fish et al. · Molecular Cancer Therapeutics · 2024 · 17 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Discovery of a VHL molecular glue degrader of GEMIN3 by Picowell RNA-seq

Jonathan W. Bushman, Weixian Deng, Kusal T. G. Samarasinghe et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2025 · 14 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +13