Sylvie Challal

Synthesis, Pharmacological and Structural Characterization, and Thermodynamic Aspects of GluA2-Positive Allosteric Modulators with a 3,4-Dihydro-2<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxide Scaffold

Ann‒Beth Nørholm, Pierre Francotte, Lars Olsen et al. · Journal of Medicinal Chemistry · 2013 · 41 citations · Full text

Structural Characterization, Chemical Biology, Pharmaceutical Chemistry +19

Total synthesis of novel conduritol related compounds capable of modulating insulin release.

David C. Billington, Françoise Perron‐Sierra, Isabelle Picard et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 39 citations

Biochemistry, Medicine, Insulin Management +7

Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2<i>H</i>-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxides

Pierre Francotte, Ann‒Beth Nørholm, Taru Deva et al. · Journal of Medicinal Chemistry · 2014 · 27 citations · Full text

Chemistry, Chemical Biology, Pharmaceutical Chemistry +17

Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors

Sylvie Bretin, Caroline Louis, Laure Seguin et al. · PLoS ONE · 2017 · 23 citations · Full text

Repetitive Glutamate Pulses, Synaptic Transmission, Neurotransmitter +26

Development of Thiophenic Analogues of Benzothiadiazine Dioxides as New Powerful Potentiators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptors

Pierre Francotte, Eric Goffin, Pierre Fraikin et al. · Journal of Medicinal Chemistry · 2013 · 21 citations

Thiophenic Analogues, Organic Chemistry, Pharmacotherapy +18