Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

Chan Hee Lee, Hyo Jin Kim, Yong Soo Lee, +17

Cell Reports

Leptin-promoted cilia assembly is critical for normal energy balance

Yu Han, Gil Myoung Kang, Kyunghee Byun, +8

Journal of Clinical Investigation

NF-κB Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia

Pil‐Geum Jang, Cherl NamKoong, Gil Myoung Kang, +13

Journal of Biological Chemistry

ImmunologyNeuroendocrinologyFood IntakeHypothalamic CircuitsLeptin-induced Anorexia +22

Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism

Gil Myoung Kang, Se Hee Min, Chan Hee Lee, +19

Cell Metabolism

Energy HomeostasisNeurophysiologyExerciseExercise PhysiologyPhysiology +8

Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway

So Young Gil, Byung‐Soo Youn, Kyunghee Byun, +12

Nature Communications

ObesityMetabolic SyndromeEnergy HomeostasisSystems BiologySignal Transduction +13

Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus

Chan Hee Lee, Do Kyeong Song, Chae Beom Park, +13

Nature Communications

Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization

Gil Myoung Kang, Yu Han, Hyuk Wan Ko, +4

Journal of Biological Chemistry

Clusterin/ApoJ enhances central leptin signaling through Lrp2‐mediated endocytosis

Kyunghee Byun, So Young Gil, Cherl NamKoong, +8

EMBO Reports

Protein FunctionSignal TransductionMolecular PhysiologySignaling PathwayEndocytic Pathway +5

Effects of Chronic NAD Supplementation on Energy Metabolism and Diurnal Rhythm in Obese Mice

Eun Roh, Gil Myoung Kang, So Young Gil, +5

Obesity

NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia.

Pil‐Geum Jang, Cherl NamKoong, Gil Myoung Kang, +13

ObesityNf-kappab ActivationNeuropeptidesPsychiatryMedicine +9