Targeted therapy in patients with PIK3CA-related overgrowth syndrome

Quitterie Venot, Thomas Blanc, S. Hadj‐Rabia, +33

Nature

Receptor Tyrosine KinasePathologyMedicinePik3ca-related Overgrowth SyndromeCancer Research +1

Sodium–glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice

Shinji Tanaka, Yuki Sugiura, Hisako Saito, +7

Kidney International

Sodium–glucose Cotransporter 2Metabolic SyndromeInhibition NormalizesBiochemistrySodium Homeostasis +13

Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells.

Jun Ohsumi, Sachiko Sakakibara, Junna Yamaguchi, +5

Endocrinology

ImmunologyPathologyInsulin SignalingInflammationMetabolic Syndrome +19

Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ

Junna Yamaguchi, Tetsuhiro Tanaka, Nobuaki Eto, +1

Kidney International

Alpelisib administration reduced lymphatic malformations in a mouse model and in patients

Florence Delestre, Quitterie Venot, Charles Bayard, +23

Science Translational Medicine

Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury

Yoshiki Higashijima, Tetsuhiro Tanaka, Junna Yamaguchi, +2

American Journal of Physiology-Renal Physiology

ImmunologyRenal InflammationAnti-inflammatory RoleInsulin SignalingInflammation +24

Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury

Shinji Tanaka, Tetsuhiro Tanaka, Takahisa Kawakami, +7

Kidney International

InflammationImmunologyRenal InflammationHydrogen PeroxideEndothelial Dysfunction +8

Anthracycline Inhibits Recruitment of Hypoxia-inducible Transcription Factors and Suppresses Tumor Cell Migration and Cardiac Angiogenic Response in the Host

Tetsuhiro Tanaka, Junna Yamaguchi, Kumi Shoji, +1

Journal of Biological Chemistry

Family Members LoxAnthracycline Inhibits RecruitmentImmunologyCardiovascular ToxicityCancer Biology +16

Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300‐interacting transactivator with Glu/Asp‐rich carboxy‐terminal domain 2 (CITED2) and suppresses the expression of hypoxia‐inducible genes in experimental CKD and uremia

Tetsuhiro Tanaka, Junna Yamaguchi, Yoshiki Higashijima, +1

The FASEB Journal

Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner

Junna Yamaguchi, Tetsuhiro Tanaka, Hisako Saito, +5

Scientific Reports