Gareth W. Harbottle

Targeting the p300/CBP Axis in Lethal Prostate Cancer

Jonathan Welti, Adam Sharp, Nigel Brooks et al. · Cancer Discovery · 2021 · 269 citations · Full text

Cycloaddition of Chiral <i>tert</i>-Butanesulfinimines with Trimethylenemethane

George Procopiou, William Lewis, Gareth W. Harbottle et al. · Organic Letters · 2013 · 36 citations

Enantioselective Synthesis, Engineering, Functionalized Chiral Pyrrolidines +9

Convergent Asymmetric Synthesis of Two Complex TRPV1 Antagonists

Kenneth J. Butcher, Steven M. Denton, Stuart Field et al. · Organic Process Research & Development · 2011 · 27 citations

Characterisation of CCS1477: A novel small molecule inhibitor of p300/CBP for the treatment of castration resistant prostate cancer.

Neil Pegg, Nigel Brooks, Jenny Worthington et al. · Journal of Clinical Oncology · 2017 · 24 citations

Androgen Receptor, Drug Target, C-myc Protein +18

Structure–activity relationships of novel non-competitive mGluR1 antagonists: A potential treatment for chronic pain

Dafydd R. Owen, Peter G. Dodd, Simon Gayton et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 21 citations · Full text

Molecular Pharmacology, Health Sciences, Biochemistry +15