Sarah E. Ewald

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

Sarah E. Ewald, Bettina L. Lee, Laura Lau et al. · Nature · 2008 · 592 citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +11

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

Sarah E. Ewald, Alex Engel, Jiyoun Lee et al. · The Journal of Experimental Medicine · 2011 · 296 citations · Full text

Innate Immune System, Immunology, Toll-like Receptor +19

NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii

Sarah E. Ewald, Joseph Chavarría‐Smith, John C. Boothroyd · Infection and Immunity · 2013 · 249 citations · Full text

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

Lena Pernas, Yaw Adomako‐Ankomah, Anjali J. Shastri et al. · PLoS Biology · 2014 · 177 citations · Full text

Transmembrane Mutations in Toll-like Receptor 9 Bypass the Requirement for Ectodomain Proteolysis and Induce Fatal Inflammation

Maria L. Mouchess, Nicholas Arpaia, Gianne Souza et al. · Immunity · 2011 · 104 citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +13