Sarah Lively

Discovery of AMG 925, a FLT3 and CDK4 Dual Kinase Inhibitor with Preferential Affinity for the Activated State of FLT3

Zhihong Li, Xianghong Wang, John Eksterowicz et al. · Journal of Medicinal Chemistry · 2014 · 70 citations · Full text

Molecular Biology, Structural Optimization, Activated State +22

Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 Diabetes

Narihiro Toda, Xiaolin Hao, Yasuyuki Ogawa et al. · ACS Medicinal Chemistry Letters · 2013 · 43 citations · Full text

Insulin Signaling, Metabolic Syndrome, Molecular Pharmacology +16

Discovery of AMG 853, a CRTH2 and DP Dual Antagonist

Jiwen Liu, An‐Rong Li, Yingcai Wang et al. · ACS Medicinal Chemistry Letters · 2011 · 33 citations · Full text

Anti-inflammatory, Inflammatory Lung Disease, Allergy +14

New potent calcimimetics: II. Discovery of benzothiazole trisubstituted ureas

Pierre Deprez, Taoues Temal, Hélène Jary et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 20 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +6

New potent calcimimetics: I. Discovery of a series of novel trisubstituted ureas

Taoues Temal, Hélène Jary, Marielle Auberval et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 14 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +9