Gilles Besin

Impact of mRNA chemistry and manufacturing process on innate immune activation

Jennifer Nelson, Elizabeth W. Sorensen, Shrutika Mintri et al. · Science Advances · 2020 · 341 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Systemic Messenger RNA Therapy as a Treatment for Methylmalonic Acidemia

An Ding, Jessica L. Schneller, Andrea Frassetto et al. · Cell Reports · 2017 · 260 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +16

Systemic mRNA Therapy for the Treatment of Fabry Disease: Preclinical Studies in Wild-Type Mice, Fabry Mouse Model, and Wild-Type Non-human Primates

Xuling Zhu, Ling Yin, Matt Theisen et al. · The American Journal of Human Genetics · 2019 · 160 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +17

Granulocyte-Macrophage Colony-Stimulating Factor Prevents Diabetes Development in NOD Mice by Inducing Tolerogenic Dendritic Cells that Sustain the Suppressive Function of CD4+CD25+ Regulatory T Cells

Simon Gaudreau, Chantal Guindi, Michaël Ménard et al. · The Journal of Immunology · 2007 · 117 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The Role of Endoplasmic Reticulum-Associated Aminopeptidase 1 in Immunity to Infection and in Cross-Presentation

Elke Firat, Loredana Saveanu, Peter Aichele et al. · The Journal of Immunology · 2007 · 115 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17