Weiyi Toy

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer

Weiyi Toy, Yang Shen, Helen Won et al. · Nature Genetics · 2013 · 1.2K citations · Full text

Breast Oncology, Hormone-resistant Breast Cancer, Breast Cancer +5

Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway

Zhiqiang Li, Pedram Razavi, Qing Li et al. · Cancer Cell · 2018 · 491 citations · Full text

Tumor Biology, Hippo Pathway, Signaling Pathway +8

Activating <i>ESR1</i> Mutations Differentially Affect the Efficacy of ER Antagonists

Weiyi Toy, Hazel M. Weir, Pedram Razavi et al. · Cancer Discovery · 2016 · 360 citations · Full text

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

Sean W. Fanning, Christopher G. Mayne, Venkatasubramanian Dharmarajan et al. · eLife · 2016 · 297 citations · Full text

Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS–ERK Signaling

Marie Will, Alice Can Ran Qin, Weiyi Toy et al. · Cancer Discovery · 2014 · 196 citations · Full text

Pi3k Inhibitors, Rapid Induction, Chemoprevention Strategy +20