Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways

Yajuan Song, Fujun Dai, Dong Zhai, +6

Angiogenesis

Breast OncologyAngiogenesisVegfr2-mediated AktMedicineCancer Growth +9

Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion

Tao Zhang, Jingjie Li, Yanmin Dong, +7

Breast Cancer Research and Treatment

Cucurbitacin E InhibitsOncologyBreast OncologyMedicinePathology +9

Design, Synthesis, and Biological Evaluation of Mitochondria-Targeted Flavone–Naphthalimide–Polyamine Conjugates with Antimetastatic Activity

Fujun Dai, Qian Li, Yuxia Wang, +6

Journal of Medicinal Chemistry

Polyamine TransporterHomospermidine MotifTumor BiologyMedicinal ChemistryBiological Evaluation +16

Indirubin inhibits tumor growth by antitumor angiogenesis <i>via</i> blocking VEGFR2‐mediated JAK/STAT3 signaling in endothelial cell

Xiaoli Zhang, Yajuan Song, Yuanyuan Wu, +8

International Journal of Cancer

ImmunologyCancer BiologyTumor AngiogenesisTumor BiologyProstate Tumor Growth +17

A Natural Small Molecule Harmine Inhibits Angiogenesis and Suppresses Tumour Growth through Activation of p53 in Endothelial Cells

Fujun Dai, Yihua Chen, Yajuan Song, +9

PLoS ONE

Tumor BiologyAngiogenesisEndothelial CellsChemoprevention StrategyMedicine +12

Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis<i>via</i>AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells

Cong Wang, Ping Ruan, Ying Zhao, +13

Oncotarget

Chemoprevention StrategyPathologyCell GrowthIntracellular PolyaminesCancer Biology +17

Synthesis of Novel Heterocyclic Ring‐Fused 18<i>β</i>‐Glycyrrhetinic Acid Derivatives with Antitumor and Antimetastatic Activity

Cheng Gao, Fujun Dai, Hai‐Wei Cui, +5

Chemical Biology & Drug Design

Pharmaceutical ScienceChemoprevention StrategyPharmacotherapyHeterocycle ChemistryNovel Heterocyclic +17

Extracellular polyamines-induced proliferation and migration of cancer cells by ODC, SSAT, and Akt1-mediated pathway

Fujun Dai, Wubei Yu, Jia Song, +3

Anti-Cancer Drugs

PathologyExtracellular Polyamines-induced ProliferationCancer BiologyTumor BiologyCancer Cell Biology +18

Antitumor Action of a Novel Histone Deacetylase Inhibitor, YF479, in Breast Cancer

Tao Zhang, Yihua Chen, Jingjie Li, +9

Neoplasia

Farrerol inhibited angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway

Fujun Dai, Lei Gao, Yuan Zhao, +2

Phytomedicine

AngiogenesisAtherosclerosisMedicineImmunologyJak2/stat3 Signal Pathway +6