Xiaohua Leng

m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

Jun Liu, Mark A. Eckert, Bryan T. Harada et al. · Nature Cell Biology · 2018 · 860 citations · Full text

Cancer Research, Akt Activity, Medicine +9

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

George F. Allan, Xiaohua Leng, Sophia Y. Tsai et al. · Journal of Biological Chemistry · 1992 · 361 citations · Full text

Molecular Biology, Conformational Modification, Molecular Pharmacology +17

The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional Silencing

Aria Baniahmad, Xiaohua Leng, Thomas P. Burris et al. · Molecular and Cellular Biology · 1995 · 247 citations · Full text

Mouse Retinoid X Receptor Contains a Separable Ligand-Binding and Transactivation Domain in Its E Region

Xiaohua Leng, Jorge C. G. Blanco, Sophia Y. Tsai et al. · Molecular and Cellular Biology · 1995 · 95 citations · Full text

Amino Acids, Molecular Regulation, Molecular Biology +18

Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor

Xiaohua Leng, Sophia Y. Tsai, Bert W. O’Malley et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1993 · 92 citations

Retinoic X Receptor, Signal Transduction, Biochemistry +12