Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

Marco Prinz, Hauke Schmidt, Alexander Mildner, +13

Immunity

InflammationAutoimmune DiseaseMedicineImmunologyVivo Functions +10

Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation

Ilona Gutcher, Moses Donkor, Qian Ma, +3

Immunity

Immune Cell DevelopmentT-regulatory CellImmunologyAutoimmunityCell Proliferation +5

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

Mirco Friedrich, Roman Sankowski, Lukas Bunse, +34

Nature Cancer

Interleukin 18–independent engagement of interleukin 18 receptor-α is required for autoimmune inflammation

Ilona Gutcher, Eduard Urich, Karina Wolter, +2

Nature Immunology

Autoimmune InflammationImmunodeficienciesImmune RegulationImmunologyImmune System +14

Foxp3+ Regulatory T Cells Promote T Helper 17 Cell Development In Vivo through Regulation of Interleukin-2

Yi Chen, Christopher J. Haines, Ilona Gutcher, +7

Immunity

InflammationCytokineDevelopmental BiologyAutoimmune DiseaseLymphocyte Development +8

Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors

Eduard Urich, Ilona Gutcher, Marco Prinz, +1

Proceedings of the National Academy of Sciences

ImmunologyImmunotherapyNeuroinflammationInflammationAutoantibodies +16

Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy

Christina Kober, Julian Roewe, Norbert Schmees, +28

Journal for ImmunoTherapy of Cancer

Comparison of Potent Kv1.5 Potassium Channel Inhibitors Reveals the Molecular Basis for Blocking Kinetics and Binding Mode

Nathalie Strutz‐Seebohm, Ilona Gutcher, Niels Decher, +3

Cellular Physiology and Biochemistry

Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes

Alexander Bachmann, Ilona Gutcher, Karin Kopp, +4

Naunyn-Schmiedeberg s Archives of Pharmacology

Cardiac MuscleXenopus OocytesMolecular PhysiologySignal TransductionHyperpolarization (Biology) +11

Abstract 4454: Identification of BAY-218, a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression

Norbert Schmees, Ilona Gutcher, Ulrike Roehn, +12

Cancer Research

Tumor ImmunosuppressionImmunologyImmune RegulationImmunoeditingBiological Therapy +20