Giorgos C. Karakousis

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Gang Chen, Alexander C. Huang, Wei Zhang et al. · Nature · 2018 · 2.7K citations · Full text

Exosomal Pd-l1 Contributes, Allergy, Autoimmune Disease +11

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Alexander C. Huang, Michael A. Postow, Robert J. Orlowski et al. · Nature · 2017 · 1.6K citations · Full text

Burden Ratio, Cancer Immunosurveillance, Medicine +8

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra McDonald et al. · Nature · 2019 · 1.5K citations

Transcriptional Regulation, T-regulatory Cell, Gene Expression +3

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

Jean‐Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem et al. · Immunity · 2020 · 974 citations · Full text

Chromatin, Transcriptional Regulation, Lineage Plasticity +11

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Alexander C. Huang, Robert Orlowski, Xiaowei Xu et al. · Nature Medicine · 2019 · 683 citations

Neoadjuvant Pd-1 Blockade, Surgical Oncology, Medicine +11