Genomic deletion of the whole IgH 3′ regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes

Christelle Vincent‐Fabert, Rémi Fiancette, Eric Pinaud, +4

Blood

Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity

Isaac Dean, Colin Y.C. Lee, Zewen Kelvin Tuong, +19

Nature Communications

The IgH 3′ regulatory region controls somatic hypermutation in germinal center B cells

Pauline Rouaud, Christelle Vincent‐Fabert, Alexis Saintamand, +7

The Journal of Experimental Medicine

In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue

Zhi Li, Zewen Kelvin Tuong, Isaac Dean, +16

The Journal of Experimental Medicine

T-regulatory CellImmunologyLymphoid TissueCd4 T Cell ResponsesImmune Cell Therapy +15

Peripheral lymph nodes contain migratory and resident innate lymphoid cell populations

Emma E. Dutton, Dominika W. Gajdasik, Claire Willis, +11

Science Immunology

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

Daniela Nasteska, Nicholas H. F. Fine, Fiona Ashford, +16

Nature Communications

Reciprocal transcription factor networks govern tissue-resident ILC3 subset function and identity

Rémi Fiancette, Conor M. Finlay, Claire Willis, +7

Nature Immunology

Signal TransductionFunctional GenomicsSignaling PathwayImmunologyGene Expression +8

Ig Synthesis and Class Switching Do Not Require the Presence of the hs4 Enhancer in the 3′ IgH Regulatory Region

Christelle Vincent‐Fabert, Véronique Truffinet, Rémi Fiancette, +3

The Journal of Immunology

Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice

Nikos E. Papaioannou, Natallia Salei, Stephan Rambichler, +20

Nature Communications

T-bet and RORα control lymph node formation by regulating embryonic innate lymphoid cell differentiation

Christina Stehle, Timo Rückert, Rémi Fiancette, +11

Nature Immunology

Developmental BiologyLymphocyte DevelopmentImmune Cell DevelopmentImmune RegulationImmunology +7