Andrea Hart

SCH 503034, a Mechanism-Based Inhibitor of Hepatitis C Virus NS3 Protease, Suppresses Polyprotein Maturation and Enhances the Antiviral Activity of Alpha Interferon in Replicon Cells

Bruce A. Malcolm, R. Liu, Frederick Lahser et al. · Antimicrobial Agents and Chemotherapy · 2006 · 318 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 282 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Western blot analysis of the human antibody response to Campylobacter jejuni cellular antigens during gastrointestinal infection

Irving Nachamkin, Andrea Hart · Journal of Clinical Microbiology · 1985 · 78 citations · Full text

Life Sciences, Immunology, Microbiology +17

Discovery and Structure−Activity Relationship of P₁−P₃ Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

Srikanth Venkatraman, Francisco Velázquez, Wanli Wu et al. · Journal of Medicinal Chemistry · 2008 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Preclinical Characterization of the Antiviral Activity of SCH 900518 (Narlaprevir), a Novel Mechanism-Based Inhibitor of Hepatitis C Virus NS3 Protease

Xiao Tong, Ashok Arasappan, Frank Bennett et al. · Antimicrobial Agents and Chemotherapy · 2010 · 46 citations

Medicine, Medicinal Chemistry, Pharmacology +17