Alena Siarheyeva

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu et al. · Nature Chemical Biology · 2011 · 527 citations

Signal Transduction, Cellular Enzymology, Biochemistry +12

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a

Feng Liu, Xin Chen, Abdellah Allali‐Hassani et al. · Journal of Medicinal Chemistry · 2009 · 236 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +17

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

Feng Liu, Xin Chen, Abdellah Allali‐Hassani et al. · Journal of Medicinal Chemistry · 2010 · 204 citations · Full text

Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

Weihong Zheng, Glorymar Ibáñez, Hong Wu et al. · Journal of the American Chemical Society · 2012 · 145 citations · Full text

Biomolecular Structure Prediction, Molecular Regulation, Epigenetic Change +22

Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

Mohammad S. Eram, Susan P. Bustos, Evelyne Lima‐Fernandes et al. · Journal of Biological Chemistry · 2014 · 116 citations · Full text

Histone Modifications, Chromatin, Chromatin Structure +11