Michal Minczuk

Mitochondrially targeted <scp>ZFN</scp> s for selective degradation of pathogenic mitochondrial genomes bearing large‐scale deletions or point mutations

Payam A. Gammage, Joanna Rorbach, Anna Vincent et al. · EMBO Molecular Medicine · 2014 · 304 citations · Full text

Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

Payam A. Gammage, Carlo Viscomi, Marie‐Lune Simard et al. · Nature Medicine · 2018 · 301 citations

Genome Instability, Mitochondrial Function, Natural Sciences +11

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

Lindsey Van Haute, Sabine Dietmann, Laura S. Kremer et al. · Nature Communications · 2016 · 245 citations · Full text

NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction

Edoardo Gaude, Christina Schmidt, Payam A. Gammage et al. · Molecular Cell · 2018 · 233 citations · Full text

Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

Cornelia Kornblum, Thomas J. Nicholls, Tobias B. Haack et al. · Nature Genetics · 2013 · 227 citations · Full text

Mitochondrial Myopathy, Genome Instability, Mitochondrial Function +8