David Acton - Concepedia

Author

David Acton

AstraZeneca (United Kingdom)

Also Known As

D. ACTON, D. G. ACTON, D.G. Acton, David Acton, David G Acton, David G. Acton

Publications

688

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (United Kingdom)University of St Andrews University of California San Diego AstraZeneca (France)Salk Institute for Biological Studies

About

David Acton is an author at AstraZeneca (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	205
2	Natural Sciences	4	4	139
3	Biochemistry	2	2	43
4	Engineering	1	1	32
5	Health Sciences	1	1	30

David Acton

Publications

432

Citations

H-Index

Page 1

	Year	Citations
Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch David Acton, Xiangyu Ren, Stefania Di Costanzo, Cell Reports	2019	103
New classes of antibacterial oxazolidinones with C-5, methylene O-Linked heterocyclic side chains Michael B. Gravestock, David Acton, Michael J Betts, Bioorganic & Medicinal Chemistry Letters Bioorganic ChemistryHeterocyclicNatural SciencesAntibacterial OxazolidinonesOrganic Chemistry	2003	59
Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer Robert H. Bradbury, David Acton, Nicola Broadbent, Bioorganic & Medicinal Chemistry Letters UrologyEndocrine-related CancerMedicineAdvanced Prostate CancerAnti-cancer Agent	2013	51
Small-molecule androgen receptor downregulators as an approach to treatment of advanced prostate cancer Robert H. Bradbury, Neil J. Hales, Alfred A. Rabow, Bioorganic & Medicinal Chemistry Letters UrologyGenitourinary CancerMedicineHormonal ReceptorAdvanced Prostate Cancer	2011	44
Tricyclic triarylethylene antiestrogens: dibenz[b,f]oxepins, dibenzo[b,f]thiepins, dibenzo[a,e]cyclooctenes, and dibenzo[b,f]thiocins David Acton, G. C. Hill, Brian S. Tait Journal of Medicinal Chemistry Hormonal ContraceptiveGynecologyOrganic ChemistryPharmacotherapyChemistry	1983	37
Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode M. Raymond V. Finlay, David Acton, David Andrews, Bioorganic & Medicinal Chemistry Letters Cyclin-dependent Kinase InhibitorsMedicinal ChemistryDrug TargetBiochemistryNatural Sciences	2008	33
Identification of an essential spinoparabrachial pathway for mechanical itch Xiangyu Ren, Shijia Liu, Amandine Virlogeux, Neuron MechanobiologyMusculoskeletal ResearchEngineeringBiomechanicsMolecular Biology	2023	32
Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine David Acton, Gareth B. Miles PLoS ONE NeurotransmitterGlia Reveals ModulationNeurotransmissionCellular NeurobiologyCellular Physiology	2015	30
Modulation of spinal motor networks by astrocyte-derived adenosine is dependent on D<sub>1</sub>-like dopamine receptor signaling David Acton, Matthew J. Broadhead, Gareth B. Miles Journal of Neurophysiology	2018	23
Differential regulation of NMDA receptors by<scp>d</scp>-serine and glycine in mammalian spinal locomotor networks David Acton, Gareth B. Miles Journal of Neurophysiology	2017	10

Page 1