The Kcnq1ot1 Long Non-Coding RNA Affects Chromatin Conformation and Expression of Kcnq1, but Does Not Regulate Its Imprinting in the Developing Heart

Lisa Korostowski, Natalie Sedlak, Nora Engel

PLoS Genetics

Early HeartGeneticsGenomic MechanismEpigeneticsDeveloping Heart +14

CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus

Nora Engel, Joanne L. Thorvaldsen, Marisa S. Bartolomei

Human Molecular Genetics

Antagonism between DNA hypermethylation and enhancer-blocking activity at the H19 DMD is uncovered by CpG mutations

Nora Engel, Adam G. West, Gary Felsenfeld, +1

Nature Genetics

Epigenetic ChangeGeneticsDna MethylationGenomic MechanismMolecular Biology +14

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

Rachael J. Werner, Bryant M. Schultz, Jacklyn Huhn, +3

Biology of Sex Differences

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

Charly R. Good, Jozef Madžo, Bela Patel, +4

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationPathologyCancer Biology +23

Three-dimensional conformation at the H19/Igf2 locus supports a model of enhancer tracking

Nora Engel, Anjali Raval, J. L. Thorvaldsen, +1

Human Molecular Genetics

Histamine as an autocrine growth factor in experimental mammary carcinomas

G. Cricco, Carlos Davio, G. Martín, +4

Inflammation Research

Tumor BiologyMalignant DiseaseMedicineCancer GrowthPathology +8

The developmental origins of sex-biased expression in cardiac development

Daniel Deegan, Reza Karbalaei, Jozef Madžo, +2

Biology of Sex Differences

Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation

Laura Barrio‐Real, Lorena Benedetti, Nora Engel, +4

Breast Cancer Research

Enhancers compete with a long non-coding RNA for regulation of the Kcnq1 domain

Bryant M. Schultz, Gwendolyn A. Gallicio, Matteo Cesaroni, +2

Nucleic Acids Research

Imprinted Kcnq1 DomainGeneticsEpigenetic ChangeEpigeneticsIntron 11 +16