Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

Carlos Silvestre-Roig, Quinte Braster, Kanin Wichapong, +36

Nature

InflammationChromatinAutoimmune DiseaseChromatin RemodelingLytic Cell Death +10

Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge–Mediated Monocyte Adhesion

Ariane Schumski, Almudena Ortega‐Gómez, Kanin Wichapong, +23

Circulation

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation

Philipp von Hundelshausen, Stijn M. Agten, Veit Eckardt, +24

Science Translational Medicine

Acute Lung InjuryChemokine BiologyImmunologyImmunologic MechanismImmune System +18

Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis

Donato Santovito, Virginia Egea, Kiril Bidzhekov, +22

Science Translational Medicine

Recruitment of classical monocytes can be inhibited by disturbing heteromers of neutrophil HNP1 and platelet CCL5

Jean-Éric Alard, Almudena Ortega‐Gómez, Kanin Wichapong, +23

Science Translational Medicine

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

Joram Huckriede, Sara Bülow Anderberg, Albert Morales, +14

Scientific Reports

Chemokines and galectins form heterodimers to modulate inflammation

Veit Eckardt, Michelle C. Miller, Xavier Blanchet, +18

EMBO Reports

Chemokine BiologyImmunologyImmune RegulationImmunologic MechanismImmune System +17

Application of Docking and QM/MM-GBSA Rescoring to Screen for Novel Myt1 Kinase Inhibitors

Kanin Wichapong, Alexander Rohe, Charlott Platzer, +4

Journal of Chemical Information and Modeling

Homology modeling and molecular dynamics simulations of Dengue virus NS2B/NS3 protease: insight into molecular interaction

Kanin Wichapong, Somsak Pianwanit, Wolfgang Sippl, +1

Journal of Molecular Recognition

Histone H3 Cleavage in Severe COVID-19 ICU Patients

Joram Huckriede, Femke de Vries, Michael Hultström, +6

Frontiers in Cellular and Infection Microbiology

Histone ModificationsHistone H3Epigenetic ChangeImmunologyPathology +16