Pietá Schofield

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Pietá Schofield, Marek Gierliński, Christian Cole et al. · RNA · 2016 · 930 citations · Full text

Engineering, Rna-seq Experiment, Genetics +23

Hypoxia induces rapid changes to histone methylation and reprograms chromatin

Michael Batie, Julianty Frost, Mark Frost et al. · Science · 2019 · 375 citations

Histone Modifications, Epigenetic Change, Genetics +21

Evaluation of tools for differential gene expression analysis by RNA-seq on a 48 biological replicate experiment

Pietá Schofield, Marek Gierliński, Christian Cole et al. · arXiv (Cornell University) · 2015 · 363 citations · Full text

Engineering, Rna-seq Experiment, Genetics +20

High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli

Silvana van Koningsbruggen, Marek Gierliński, Pietá Schofield et al. · Molecular Biology of the Cell · 2010 · 327 citations · Full text

Nuclear Structure, Genetics, Molecular Biology +17

A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization

Triantaffyllos Gkikopoulos, Pietá Schofield, Vijender Singh et al. · Science · 2011 · 298 citations · Full text

Snf2-related Nucleosome-spacing Enzymes, Genetics, Molecular Biology +18