Kaori Misawa

Involvement of μ-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa

Kenjiro Matsumoto, Yoshio Hatori, Toshihiko Murayama et al. · European Journal of Pharmacology · 2006 · 95 citations

Pain Disorders, Health Sciences, Pain Medicine +11

New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Application to the Preparation of Potent Opioid Receptor Agonists with a Corynanthe Skeleton

Hiromitsu Takayama, Kaori Misawa, Naoki Okada et al. · Organic Letters · 2006 · 58 citations

Ethylene Glycol, Organic Chemistry, Pharmacotherapy +17

MGM-9 [(E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro-1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate], a derivative of the indole alkaloid mitragynine: A novel dual-acting μ- and κ-opioid agonist with potent antinociceptive and weak rewarding effects in mice

Kenjiro Matsumoto, Hiromitsu Takayama, Minoru Narita et al. · Neuropharmacology · 2008 · 54 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmacological Study +11

A new indole alkaloid, 7-hydroxyspeciociliatine, from the fruits of Malaysian Mitragyna speciosa and its opioid agonistic activity

Mariko Kitajima, Kaori Misawa, Noriyuki Kogure et al. · Journal of Natural Medicines · 2005 · 51 citations

New Indole Alkaloid, Opioid Agonistic Activity, Pharmacological Study +6

Orally Active Opioid μ/δ Dual Agonist MGM-16, a Derivative of the Indole Alkaloid Mitragynine, Exhibits Potent Antiallodynic Effect on Neuropathic Pain in Mice

Kenjiro Matsumoto, Minoru Narita, Naotaka Muramatsu et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 49 citations · Full text