Jennifer A. Lacap

Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer

Uzma Asghar, Alexis R. Barr, Ros Cutts et al. · Clinical Cancer Research · 2017 · 283 citations · Full text

Life Sciences, Cell Biology, Oncology +16

An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

Thijs J. Hagenbeek, Marc Hafner, Rana Mroue et al. · Nature Cancer · 2023 · 195 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +17

Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

Guangmin Li, Jun Guo, Ben‐Quan Shen et al. · Molecular Cancer Therapeutics · 2018 · 184 citations

Medicine, Oncology, Pharmacology +17

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling

Jeffrey K. Holden, James J. Crawford, Cameron L. Noland et al. · Cell Reports · 2020 · 173 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis

Gail D. Lewis Phillips, Merry Nishimura, Jennifer A. Lacap et al. · Breast Cancer Research and Treatment · 2017 · 64 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17