Anna Guan

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Renee D. Paulsen, Deena V. Soni, Roy Wollman et al. · Molecular Cell · 2009 · 570 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

The effect of LRRK2 loss-of-function variants in humans

Nicola Whiffin, Irina M. Armean, Aaron Kleinman et al. · Nature Medicine · 2020 · 113 citations · Full text

Life Sciences, Genetics, Neuroscience +13

Biochemical Evidence for a Nuclear Modifier Allele (A10S) in TRMU (Methylaminomethyl-2-thiouridylate-methyltransferase) Related to Mitochondrial tRNA Modification in the Phenotypic Manifestation of Deafness-associated 12S rRNA Mutation

Feilong Meng, Xiaohui Cang, Yanyan Peng et al. · Journal of Biological Chemistry · 2017 · 51 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Precision medical image hash retrieval by interpretability and feature fusion

Anna Guan, Li Liu, Li Liu et al. · Computer Methods and Programs in Biomedicine · 2022 · 26 citations

Computing, Biomedical Informatics, Computer Science +14

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

Nicola Whiffin, Irina M. Armean, Aaron Kleinman et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 17 citations · Full text

Life Sciences, Genetics, Neuroscience +14