Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety

Tomasz Plech, Monika Wujec, Agata Siwek, +2

European Journal of Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryHeterocyclicNatural Sciences3-Chlorophenyl Moiety +6

The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test

Bernadeta Szewczyk, Ewa Poleszak, Andrzej Wróbel, +9

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Psychoactive DrugPsychiatryAntidepressant EffectMedicinePhysiology +11

Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors

Paweł Zajdel, Krzysztof Marciniec, Andrzej Maślankiewicz, +12

European Journal of Medicinal Chemistry

Isoquinoline-sulfonamide AnalogsMedicinal ChemistryPsychoactive DrugPsychiatryMedicine +10

The involvement of NMDA and AMPA receptors in the mechanism of antidepressant-like action of zinc in the forced swim test

Bernadeta Szewczyk, Ewa Poleszak, Magdalena Sowa-Kućma, +9

Amino Acids

Psychoactive DrugAntidepressant-like ActionPsychiatryNeurophysiologyMedicine +10

Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT 6 receptor antagonists. Design, synthesis and biological evaluation

Anna Więckowska, Marcin Kołaczkowski, Adam Bucki, +14

European Journal of Medicinal Chemistry

Molecular PharmacologyNeurodegenerative DiseasesDrug TargetAlzheimer's DiseaseNovel Multi-target-directed Ligands +9

Antidepressant-like activity of magnesium in the chronic mild stress model in rats: alterations in the NMDA receptor subunits

Bartłomiej Pochwat, Bernadeta Szewczyk, Magdalena Sowa-Kućma, +6

The International Journal of Neuropsychopharmacology

Antidepressant-like ActivityCms AnimalsPsychopharmacologyExperimental PharmacologySocial Sciences +16

Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives

Agata Siwek, Joanna Stefańska, Katarzyna Dzitko, +1

Journal of Molecular Modeling

Antidepressant-like effects of ketamine, norketamine and dehydronorketamine in forced swim test: Role of activity at NMDA receptor

Kinga Sałat, Agata Siwek, Gabriela Starowicz, +5

Neuropharmacology

Psychoactive DrugPsychiatryAntidepressant-like EffectsMedicineDepression +8

Development of the 1,2,4-triazole-based anticonvulsant drug candidates acting on the voltage-gated sodium channels. Insights from in-vivo, in-vitro, and in-silico studies

Barbara Kaproń, Jarogniew J. Łuszczki, Anita Płazińska, +13

European Journal of Pharmaceutical Sciences

NeurophysiologyMedicineAnesthetic MechanismIon ChannelsNeuropharmacology +7

Novel Arylsulfonamide Derivatives with 5-HT₆/5-HT₇Receptor Antagonism Targeting Behavioral and Psychological Symptoms of Dementia

Marcin Kołaczkowski, Monika Marcinkowska, Adam Bucki, +10

Journal of Medicinal Chemistry