Joris W. De Schutter

Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells

Yih‐Shyan Lin, Jaeok Park, Joris W. De Schutter et al. · Journal of Medicinal Chemistry · 2012 · 52 citations · Full text

Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition

Chun Yuen Leung, Jaeok Park, Joris W. De Schutter et al. · Journal of Medicinal Chemistry · 2013 · 46 citations · Full text

Sclerostin, Chemical Biology, Pharmaceutical Chemistry +18

Toward a computational tool predicting the stereochemical outcome of asymmetric reactions: Development of the molecular mechanics‐based program ACE and application to asymmetric epoxidation reactions

Nathanaël Weill, Christopher R. Corbeil, Joris W. De Schutter et al. · Journal of Computational Chemistry · 2011 · 36 citations

Engineering, Computational Tool, Organic Chemistry +18

Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases

Joris W. De Schutter, Jaeok Park, Chun Yuen Leung et al. · Journal of Medicinal Chemistry · 2014 · 33 citations · Full text

Molecular Biology, Neurochemical Biomarkers, Chemical Biology +18

Synthesis of new tetracyclic azaheteroaromatic cores via auto-tandem Pd-catalyzed and one-pot Pd- and Cu-catalyzed double C–N bond formation

Tom R. M. Rauws, Claudio Biancalani, Joris W. De Schutter et al. · Tetrahedron · 2010 · 27 citations

Chemical Engineering, Novel Organocatalysts, Engineering +5