Joris W. De Schutter

Author

McGill University

Also Known As

C.-Y. Leung, J. Schutter, J.W. De Schutter, Joris W De Schutter, Joris W. De Schutter, Y.-S. Lin

Publications

307

Citations

H-Index

Concepts

All Affiliations

McGill University Royal Victoria Hospital

About

Joris W. De Schutter is an author at McGill University specializing in natural sciences, biochemistry, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	6	6	165
2	Biochemistry	6	6	165
3	Medicine	5	5	129
4	Engineering	2	2	63
5	Biomolecular Engineering	1	1	36

Joris W. De Schutter

Publications

289

Citations

H-Index

Page 1

	Year	Citations
Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells Yih‐Shyan Lin, Jaeok Park, Joris W. De Schutter, Journal of Medicinal Chemistry	2012	52
Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition Chun Yuen Leung, Jaeok Park, Joris W. De Schutter, Journal of Medicinal Chemistry SclerostinChemical BiologyPharmaceutical ChemistryThienopyrimidine BisphosphonateOsteoporosis	2013	46
Toward a computational tool predicting the stereochemical outcome of asymmetric reactions: Development of the molecular mechanics‐based program ACE and application to asymmetric epoxidation reactions Nathanaël Weill, Christopher R. Corbeil, Joris W. De Schutter, Journal of Computational Chemistry EngineeringComputational ToolOrganic ChemistryChemistryNovel Organocatalysts	2011	36
Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases Joris W. De Schutter, Jaeok Park, Chun Yuen Leung, Journal of Medicinal Chemistry Molecular BiologyNeurochemical BiomarkersChemical BiologyMedicinal ChemistryAlzheimer's Disease	2014	33
Synthesis of new tetracyclic azaheteroaromatic cores via auto-tandem Pd-catalyzed and one-pot Pd- and Cu-catalyzed double C–N bond formation Tom R. M. Rauws, Claudio Biancalani, Joris W. De Schutter, Tetrahedron Chemical EngineeringNovel OrganocatalystsEngineeringOne-pot Pd-Organic Chemistry	2010	27
Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme’s active site closure Jaeok Park, Yih‐Shyan Lin, Joris W. De Schutter, BMC Structural Biology	2012	26
Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase Dimitrios Gritzalis, Jaeok Park, Wei Chiu, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicineNatural SciencesEnzyme CatalysisStructural Elements	2015	19
Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from <i>Campylobacter jejuni</i> Joris W. De Schutter, James P. Morrison, Michael J. Morrison, Journal of Medicinal Chemistry	2017	19
Novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase Joris W. De Schutter, Serge Zaretsky, Sarah Welbourn, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPharmaceutical ChemistryBiochemistryNatural SciencesMedicine	2010	16
Design of potent bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase via targeted interactions with the active site ‘capping’ phenyls Joris W. De Schutter, Joseph R. Shaw, Yih‐Shyan Lin, Bioorganic & Medicinal Chemistry Potent Bisphosphonate InhibitorsTargeted InteractionsBiochemistryMedicineNatural Sciences	2012	15

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