Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey, +22

Nature Medicine

Neurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseSynaptic SignalingMedicine +11

Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions

Laura Magri, Marco Cambiaghi, Manuela Cominelli, +9

Cell stem cell

Developmental BiologyMedicineNeural Stem CellNeuroscienceMtor Pathway +3

Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis

Stefania Mazzoleni, Letterio S. Politi, Mauro Pala, +8

Cancer Research

<scp>MET</scp> inhibition overcomes radiation resistance of glioblastoma stem‐like cells

Francesca De Bacco, Antonio D’Ambrosio, Elena Casanova, +15

EMBO Molecular Medicine

Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme

Anna Rosati, Pietro Luigi Poliani, Alice Todeschini, +8

Neuro-Oncology

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

Ashwin Narayanan, Filippo Gagliardi, Alberto L. Gallotti, +22

Cell Death and Differentiation

Ndrg1 ExpressionTranscriptional Subgroup AffiliationGbm DifferentiationGliomaTumor Biology +17

Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models

Laura Magri, Manuela Cominelli, Marco Cambiaghi, +5

Disease Models & Mechanisms

Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients

Aisha V. Sauer, Raisa Jofra Hernández, Francesca Fumagalli, +24

Scientific Reports

EBF1 is expressed in pericytes and contributes to pericyte cell commitment

Francesca Pagani, Elisa Tratta, Patrizia Dell’Era, +2

Histochemistry and Cell Biology

EGFR Amplified and Overexpressing Glioblastomas and Association With Better Response to Adjuvant Metronomic Temozolomide

Manuela Cominelli, Salvatore Grisanti, Stefania Mazzoleni, +16

JNCI Journal of the National Cancer Institute