Nicole Bertoletti

First Structure–Activity Relationship of 17β-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme

Florian Braun, Nicole Bertoletti, Gabriele Möller et al. · Journal of Medicinal Chemistry · 2016 · 30 citations · Full text

Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV

Shalley N. Kudalkar, Irfan Ullah, Nicole Bertoletti et al. · Antiviral Research · 2019 · 27 citations · Full text

Medicine, Human Retrovirus, Antiviral Drug Development +8

Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead

Joseph A. Ippolito, Haichan Niu, Nicole Bertoletti et al. · ACS Medicinal Chemistry Letters · 2021 · 24 citations · Full text

Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV‐1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine

Nicole Bertoletti, Albert H. Chan, Raymond F. Schinazi et al. · Protein Science · 2019 · 23 citations · Full text

Viral Polymerase Structure, Molecular Biology, Antiviral Drug +17

Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention

S.G. Krimmer, Nicole Bertoletti, Yoshihisa Suzuki et al. · Proceedings of the National Academy of Sciences · 2023 · 20 citations · Full text

Lineage Plasticity, Signal Transduction, Signaling Pathway +13