Interferon‐γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor‐associated macrophages

Dorothée Duluc, Murielle Corvaisier, Simon Blanchard, +7

International Journal of Cancer

Tumor-associated MacrophagesImmunologyImmunologic MechanismImmune SystemImmunotherapy +14

IL-34 Induces the Differentiation of Human Monocytes into Immunosuppressive Macrophages. Antagonistic Effects of GM-CSF and IFNγ

Etienne Foucher, Simon Blanchard, Laurence Preisser, +5

PLoS ONE

Dc SubsetsImmune RegulationImmunologyImmunologic MechanismCd4 T Cell Responses +20

IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation

Murielle Corvaisier, Yves Delneste, Henry Jeanvoine, +9

PLoS Biology

IL‐34 and macrophage colony‐stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells

Laurence Preisser, Charline Miot, Hélène Le Guillou‐Guillemette, +13

Hepatology

The Tachykinins Substance P and Hemokinin-1 Favor the Generation of Human Memory Th17 Cells by Inducing IL-1β, IL-23, and TNF-Like 1A Expression by Monocytes

Pierre Cunin, Antoine Caillon, Murielle Corvaisier, +5

The Journal of Immunology

Adaptive Immune SystemImmune RegulationImmunologyTachykinins Substance PImmunologic Mechanism +20

Lactic Acidosis Together with GM-CSF and M-CSF Induces Human Macrophages toward an Inflammatory Protumor Phenotype

Léa Paolini, Clément Adam, Céline Beauvillain, +21

Cancer Immunology Research

Histamine and prostaglandin E₂up‐regulate the production of Th2‐attracting chemokines (CCL17 and CCL22) and down‐regulate IFN‐γ‐induced CXCL10 production by immature human dendritic cells

Anne McIlroy, Gersende Caron, Simon Blanchard, +5

Immunology

IL-26 Confers Proinflammatory Properties to Extracellular DNA

Caroline Poli, Jean‐François Augusto, Jonathan Dauvé, +15

The Journal of Immunology

IL‐34‐ and M‐CSF‐induced macrophages switch memory T cells into Th17 cells via membrane IL‐1α

Etienne Foucher, Simon Blanchard, Laurence Preisser, +4

European Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismCd4 T Cell ResponsesM‐csf‐induced Macrophages +16

IL-26 is overexpressed in chronically HCV-infected patients and enhances TRAIL-mediated cytotoxicity and interferon production by human NK cells

Charline Miot, Élodie Beaumont, Dorothée Duluc, +16

Gut