Effects of antidepressants on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration

Yuta Ohgi, Takashi Futamura, Tetsuro Kikuchi, +1

Pharmacology Biochemistry and Behavior

PsychoneuroimmunologyPsychiatryMedicinePsychotropic MedicationLipopolysaccharide Administration +9

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis

Noriko Yoshimi, Takashi Futamura, Sarah E. Bergen, +11

Molecular Psychiatry

Mitochondrial DysfunctionCerebrospinal Fluid MetabolomicsNeurophysiological BiomarkersNeurochemical BiomarkersCsf Levels +15

Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation

Min Ma, Qian Ren, Chun Yang, +6

Psychopharmacology

Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling

Min Ma, Qian Ren, Chun Yang, +6

Scientific Reports

Global Trends in Alzheimer Disease Clinical Development: Increasing the Probability of Success

Haruhiko Sugino, Akihito Watanabe, Naoki Amada, +4

Clinical Therapeutics

Alzheimer's DiseaseVascular Cognitive DisorderDementiaVascular DementiaGlobal Trends +5

Effects of brexpiprazole, a novel serotonin-dopamine activity modulator, on phencyclidine-induced cognitive deficits in mice: A role for serotonin 5-HT1A receptors

Noriko Yoshimi, Yūkō Fujita, Yuta Ohgi, +3

Pharmacology Biochemistry and Behavior

NeuropsychologyPsychoactive DrugCognitive NeuroscienceMedicineSerotonin 5-Ht1a Receptors +8

Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin–dopamine activity modulator: A role for serotonin 5-HT1A and 5-HT2A receptors

Tamaki Ishima, Takashi Futamura, Yuta Ohgi, +3

European Neuropsychopharmacology

Psychotropic MedicationNeurotransmitterPsychopharmacologyCell CulturePharmacotherapy +16

Brexpiprazole has a low risk of dopamine D₂ receptor sensitization and inhibits rebound phenomena related to D₂ and serotonin 5‐HT_2A receptors in rats

Naoki Amada, Hitomi Akazawa, Yuta Ohgi, +5

Neuropsychopharmacology Reports

Increased BDNF-TrkB signaling in the nucleus accumbens plays a role in the risk for psychosis after cannabis exposure during adolescence

Chao Dong, Z. Ryan Tian, Kai Zhang, +8

Pharmacology Biochemistry and Behavior