HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity

Shiying Wu, Qian Zhang, Fei Zhang, +14

Nature Cell Biology

Sting SignallingViral ImmunityImmunologyAntitumour ImmunityImmunologic Mechanism +6

YAP drives fate conversion and chemoresistance of small cell lung cancer

Qingzhe Wu, Jingxin Guo, Yuning Liu, +12

Science Advances

Notch Signaling Controls Transdifferentiation of Pulmonary Neuroendocrine Cells in Response to Lung Injury

Erica Yao, Chuwen Lin, Qingzhe Wu, +3

Stem Cells

Loss of <scp>VGLL</scp> 4 suppresses tumor <scp>PD</scp> ‐L1 expression and immune evasion

Ailing Wu, Qingzhe Wu, Yujie Deng, +7

The EMBO Journal

Immune EvasionCancer ImmunosurveillanceMedicineImmunologyTumor Immunity +7

MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function

Jinqiu Lu, Liansheng Liu, Mingjie Zheng, +6

Oncogene

Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice

Xiaoling Li, Liansheng Liu, Ran Li, +6

Journal of Biological Chemistry

MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway

Jinqiu Lu, Zonghao Hu, Yujie Deng, +3

Journal of Biological Chemistry

Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma

Hai Song, Chuwen Lin, Erica Yao, +4

Journal of Biological Chemistry

Single-cell and spatial proteo-transcriptomic profiling reveals immune infiltration heterogeneity associated with neuroendocrine features in small cell lung cancer

Ying Jin, Yuefeng Wu, Alexandre Reuben, +11

Cell Discovery

The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular Trafficking

Liansheng Liu, Jinqiu Lu, Xiaoling Li, +5

Cell Reports