Vestibular defects in head-tilt mice result from mutations in<i>Nox3</i>, encoding an NADPH oxidase

Rainer Paffenholz, Rebecca A. Bergstrom, Francesca Pasutto, +11

Genes & Development

Experimental BiologyNadph OxidaseGeneticsCytoskeletonRedox Biology +21

Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis

Matthew A. Loberg, Rebecca K. Bell, Leslie O. Goodwin, +8

Leukemia

Hematologic MalignancyNpm1 MutationGeneticsAggressive MpdCancer Biology +16

Promoter specificity mediates the independent regulation of neighboring genes.

Christopher Merli, David E. Bergstrom, Jennifer A. Cygan, +1

Genes & Development

ChromatinTranscriptional RegulationSystems BiologyDevelopmental BiologyPromoter Specificity +13

Mutation discovery in mice by whole exome sequencing

Heather Fairfield, Griffith J Gilbert, Mary Barter, +29

Genome biology

Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice

Yoko Nakano, Chantal M. Longo-Guess, David E. Bergstrom, +3

Journal of Clinical Investigation

Related function of mouse SOX3, SOX9, and SRY HMG domains assayed by male sex determination

David E. Bergstrom, Maureen Young, K. Albrecht, +1

genesis

SpermatogenesisRelated FunctionSry HmgGeneticsGenomic Mechanism +20

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, +35

Genome Research

Exome SequencingGeneticsGenetic EpidemiologyPathologyDisease Gene Identification +19

Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

Manju Sharma, Anuj Srivastava, Heather Fairfield, +3

eLife

SpermatogenesisGeneticsReproductive BiologyEpigeneticsFertilisation +15

A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9

Chantal M. Longo-Guess, Leona H. Gagnon, David E. Bergstrom, +1

Hearing Research

Knockout MouseMolecular NeuroscienceSignal TransductionGenetic DisorderGenetics +8

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology

Kristina Palmer, Heather Fairfield, Suhaib Borgeia, +11

Developmental Biology

BiologyDevelopmental BiologyCraniofacial DevelopmentMorphogenesisCraniofacial Growth +6