The harlequin mouse mutation downregulates apoptosis-inducing factor

Jeffrey A. Klein, Chantal M. Longo-Guess, Marlies P. Rossmann, +5

Nature

Knockout MouseApoptosisCell DeathMedicineCell Biology +2

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

Jeong-Woong Lee, Kirk Beebe, Leslie A. Nangle, +7

Nature

Neurodegenerative DiseasesMolecular BiologyProtein MisfoldingEditing-defective Trna SynthetaseMolecular Neurobiology +2

Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP

Lihong Zhao, Chantal M. Longo-Guess, Belinda S. Harris, +2

Nature Genetics

Knockout MouseWoozy Mutant MouseNeurodegenerative DiseasesGeneticsAutophagy +5

Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice

Kelly L. Kane, Chantal M. Longo-Guess, Leona H. Gagnon, +3

Hearing Research

Genetic Background EffectsGenetic DisorderMedicineGeneticsAudiology +12

The Chloride Intracellular Channel Protein CLIC5 Is Expressed at High Levels in Hair Cell Stereocilia and Is Essential for Normal Inner Ear Function

Leona H. Gagnon, Chantal M. Longo-Guess, Mark Berryman, +5

Journal of Neuroscience

Deletion in Catna2, encoding αN-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation

Chankyu Park, William A. Falls, Jacqueline H. Finger, +2

Nature Genetics

Neurodegenerative DiseasesSynaptic PlasticityMolecular NeuroscienceDevelopmental BiologyNeuroanatomy +10

The R109H Variant of Fascin-2, a Developmentally Regulated Actin Crosslinker in Hair-Cell Stereocilia, Underlies Early-Onset Hearing Loss of DBA/2J Mice

J.-B. Shin, Chantal M. Longo-Guess, Leona H. Gagnon, +8

Journal of Neuroscience

Mutation of the Cyba gene encoding p22phox causes vestibular and immune defects in mice

Yoko Nakano, Chantal M. Longo-Guess, David E. Bergstrom, +3

Journal of Clinical Investigation

A missense mutation in the previously undescribed gene <i>Tmhs</i> underlies deafness in hurry-scurry ( <i>hscy</i> ) mice

Chantal M. Longo-Guess, Leona H. Gagnon, Susan A. Cook, +3

Proceedings of the National Academy of Sciences

Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell polarity

Daniel J. Jagger, Gayle B. Collin, John J. Kelly, +9

Human Molecular Genetics

Hair CellsAlström SyndromeAmyotrophic Lateral SclerosisDevelopmental BiologyEpendyma +13