Mark Ruben

Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses

Kathleen Lehmann, Anastasia Gulyaeva, Jessika C. Zevenhoven-Dobbe et al. · Nucleic Acids Research · 2015 · 249 citations · Full text

Life Sciences, Biology, Molecular Biology +17

Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities

Lianne I. Willems, Nan Li, Bogdan I. Florea et al. · Angewandte Chemie International Edition · 2012 · 113 citations

Pharmacy, Biochemistry, Molecular Biology +9

Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS

Nan Li, C.J. Kuo, Guillem Paniagua et al. · Nature Protocols · 2013 · 87 citations

Life Sciences, Biochemistry, Molecular Biology +16

Synthesis of <scp>l</scp>-<i>altro</i>-1-Deoxynojirimycin, <scp>d</scp>-<i>allo-</i>1-Deoxynojirimycin, and <scp>d</scp>-<i>galacto-</i>1-Deoxynojirimycin from a Single Chiral Cyanohydrin

Adrianus M. C. H. van den Nieuwendijk, Mark Ruben, Sander E. Engelsma et al. · Organic Letters · 2010 · 36 citations

Pharmacy, Medicinal Chemistry, Biocatalysis +12

Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones

Wouter A. van der Linden, Lianne I. Willems, Tamer B. Shabaneh et al. · Organic & Biomolecular Chemistry · 2011 · 31 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +15