Pentacyclic Triterpene Distribution in Various Plants – Rich Sources for a New Group of Multi-Potent Plant Extracts

Sebastian Jäger, Holger Trojan, Thomas Kopp, +2

Molecules

BiochemistryCharacterised PlantMedicineNew GroupAccelerated Solvent Extraction +10

A Preliminary Pharmacokinetic Study of Betulin, the Main Pentacyclic Triterpene from Extract of Outer Bark of Birch (Betulae alba cortex)

Sebastian Jäger, Melanie N. Laszczyk, Armin Scheffler

Molecules

Preliminary Pharmacokinetic StudyDermatologySesame OilPharmacological StudyPhytopharmacology +15

Solubility Studies of Oleanolic Acid and Betulinic Acid in Aqueous Solutions and Plant Extracts of <i>Viscum album</i> L.

Sebastian Jäger, Karin Winkler, Uwe Pfüller, +1

Planta Medica

Characterization and screening of IgG binding to the neonatal Fc receptor

Tobias Neuber, Katrin Frese, Jan Jaehrling, +11

mAbs

Immunocytochemical TechniqueImmunologyFcrn BindingSignaling PathwayBioanalysis +14

Physical, Chemical and Pharmacological Characterization of a New Oleogel-Forming Triterpene Extract from the Outer Bark of Birch (Betulae Cortex)

Melanie N. Laszczyk, Sebastian Jäger, Birgit Simon-Haarhaus, +2

Planta Medica

Medicinal ChemistryPharmacological CharacterizationPolyphenolicsBiochemistryBioassay-guided Isolation +11

GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway

Susann Kleinsimon, Enya Longmuss, Jana Rolff, +4

Scientific Reports

α‐secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation

Sebastian Jäger, Stefanie Leuchtenberger, Anne Marie Martin, +9

Journal of Neurochemistry

Neurodegenerative DiseasesProtein SecretionAlzheimer's DiseaseBiochemistryNatural Sciences +13

A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo

Catharina Delebinski, Monika Twardziok, Susann Kleinsimon, +6

PLoS ONE

AllergyChemoprevention StrategyBioassay-guided IsolationMedicineCombination Viscumtt +12

Amyloid Precursor-like Protein 1 Influences Endocytosis and Proteolytic Processing of the Amyloid Precursor Protein

Stephanie Neumann, Susanne Schöbel, Sebastian Jäger, +4

Journal of Biological Chemistry

Protein SecretionEctodomain SheddingLow DensityAmyloid Precursor ProteinAlzheimer's Disease +14

Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma

Monika Twardziok, Susann Kleinsimon, Jana Rolff, +4

PLoS ONE