Enrica Diodato

An exploratory double‐blind, randomized clinical trial with selisistat, a <scp>SirT1</scp> inhibitor, in patients with <scp>H</scp>untington's disease

Sigurd D. Süßmuth, Salman Haider, G. Bernhard Landwehrmeyer et al. · British Journal of Clinical Pharmacology · 2014 · 161 citations · Full text

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

M.R. Smith, Adeela Syed, Tamás Lukácsovich et al. · Human Molecular Genetics · 2014 · 141 citations · Full text

Histone Modifications, Cell Death, Molecular Biology +20

Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1

Carla Scali, Filippo Caraci, Marco Gianfriddo et al. · Neurobiology of Disease · 2006 · 125 citations · Full text

Neurodegenerative Diseases, Signal Transduction, Tau Phosphorylation +11

Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically

Mariagrazia Grilli, Enrica Diodato, Gianluca Lozza et al. · Proceedings of the National Academy of Sciences · 2000 · 45 citations · Full text

Cell Death, Neurochemical Biomarkers, Neurotransmission +19

Aryl azoles with neuroprotective activity—Parallel synthesis and attempts at target identification

Giuseppe Cocconcelli, Enrica Diodato, Andrea Caricasole et al. · Bioorganic & Medicinal Chemistry · 2007 · 45 citations

Biochemistry, Medicine, Drug Discovery +5