Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent

Nigel H. Greig, Tadanobu Utsuki, Donald K. Ingram, +12

Proceedings of the National Academy of Sciences

β-Amyloid-Induced Inflammation and Cholinergic Hypofunction in the Rat Brain in Vivo: Involvement of the p38MAPK Pathway

Maria Grazia Giovannini, Carla Scali, Costanza Prosperi, +5

Neurobiology of Disease

InflammationNeurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceMedicine +12

Increased Dickkopf‐1 expression in transgenic mouse models of neurodegenerative disease

Maria Cristina Rosi, Ilaria Luccarini, Cristina Grossi, +8

Journal of Neurochemistry

Transgenic Mouse ModelsNeurochemical BiomarkersSynaptic SignalingSocial SciencesNeurobiology Of Disease +15

Differential effects of amyloid peptides β-(1–40) and β-(25–35) injections into the rat nucleus basalis

Lisa Giovannelli, Fiorella Casamenti, Carla Scali, +2

Neuroscience

Neurodegenerative DiseasesDifferential EffectsAlzheimer's DiseaseMedicineNeuropharmacology +8

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

M.R. Smith, Adeela Syed, Tamás Lukácsovich, +23

Human Molecular Genetics

Histone ModificationsCell DeathMolecular BiologyMultiple AnimalTranscriptional Regulation +18

Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice

Arianna Bellucci, Ilaria Luccarini, Carla Scali, +4

Neurobiology of Disease

NeurophysiologyNeuroanatomyPhysiologyCholinergic DysfunctionNeuroprotection +6

Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1

Carla Scali, Filippo Caraci, Marco Gianfriddo, +8

Neurobiology of Disease

Neurodegenerative DiseasesSignal TransductionTau PhosphorylationSignaling PathwayNeuronal Cell Death +9

Interleukin-1β activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease

Fiorella Casamenti, Costanza Prosperi, Carla Scali, +4

Neuroscience

Glial BiologyNeurodegenerative DiseasesNitric Oxide ProductionAlzheimer's DiseaseMolecular Neuroscience +11

Selective muscarinic antagonists differentially affect in vivo acetylcholine release and memory performances of young and aged rats

Maria Giuliana Vannucchi, Carla Scali, Silvia R. Kopf, +2

Neuroscience

NeurophysiologyMedicineSelective Muscarinic AntagonistsPhysiologyAged Rats +10

Effect of metrifonate on extracellular brain acetylcholine and object recognition in aged rats

Carla Scali, Maria Grazia Giovannini, Luciano Bartolini, +4

European Journal of Pharmacology

NeuropsychologyAlzheimer's DiseaseBrain FunctionNeurophysiologyCognitive Neuroscience +9