Leticia G. León

MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity

Elisa Giovannetti, Niccola Funel, Godefridus J. Peters et al. · Cancer Research · 2010 · 453 citations · Full text

Pancreatic Cancer, Medicine, Gemcitabine Resistance +13

Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer

Jin‐Hyeok Hwang, Johannes Voortman, Elisa Giovannetti et al. · PLoS ONE · 2010 · 290 citations · Full text

Discovery of <i>N</i>-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells

Carlotta Granchi, Sarabindu Roy, Chiara Giacomelli et al. · Journal of Medicinal Chemistry · 2011 · 215 citations · Full text

Bioorganic Chemistry, Aldo-keto Reductase, Metabolic Remodeling +19

Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing

Maria Rovithi, Amir Avan, Niccola Funel et al. · Scientific Reports · 2017 · 88 citations · Full text

Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer

Daniela Massihnia, Amir Avan, Niccola Funel et al. · Journal of Hematology & Oncology · 2017 · 84 citations · Full text