Ryan L. Ragland

Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in <i>BRCA</i> -Mutant Ovarian Cancer Models

Hyoung Kim, Erin George, Ryan L. Ragland et al. · Clinical Cancer Research · 2016 · 287 citations · Full text

Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner

Oren Gilad, Barzin Y. Nabet, Ryan L. Ragland et al. · Cancer Research · 2010 · 230 citations · Full text

Atr Suppression, Genetics, Cell Cycle +16

Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR

David W. Schoppy, Ryan L. Ragland, Oren Gilad et al. · Journal of Clinical Investigation · 2011 · 184 citations · Full text

Atr Suppression, Oncogenic Stress, Oncogenic Ras +11

Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants

Martin F. Arlt, Jennifer G. Mullé, Valerie M. Schaibley et al. · The American Journal of Human Genetics · 2009 · 150 citations · Full text

Genome Instability, Allelic Variant, Somatic Variant +10

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

J. Kevin Hicks, Colleen L. Chute, Michelle T. Paulsen et al. · Molecular and Cellular Biology · 2009 · 126 citations · Full text