Adam Kashishian

CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability

Brian J. Lannutti, Sarah Meadows, Sarah E. M. Herman et al. · Blood · 2010 · 718 citations · Full text

Medicine, Oncology, Pharmacology +11

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

Wei Li, Riko Nishimura, Adam Kashishian et al. · Molecular and Cellular Biology · 1994 · 463 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.

Robert J. Lechleider, Satoru Sugimoto, Anton M. Bennett et al. · Journal of Biological Chemistry · 1993 · 319 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.

Adam Kashishian, Andrius Kazlauskas, Jonathan A. Cooper · The EMBO Journal · 1992 · 318 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

p110δ, a Novel Phosphatidylinositol 3-Kinase Catalytic Subunit That Associates with p85 and Is Expressed Predominantly in Leukocytes

David Chantry, Anne B. Vojtek, Adam Kashishian et al. · Journal of Biological Chemistry · 1997 · 250 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12