Isabel Leal

dUTPase as a Platform for Antimalarial Drug Design: Structural Basis for the Selectivity of a Class of Nucleoside Inhibitors

Jean L. Whittingham, Isabel Leal, Corinne Nguyen et al. · Structure · 2005 · 99 citations · Full text

Medicinal Chemistry, Antiparasitic Agent, Medicine +13

Design, Synthesis, and Evaluation of Inhibitors of Trypanosomal and Leishmanial Dihydrofolate Reductase

Shafinaz F. Chowdhury, Victor Bernier Villamor, Ramón Hurtado‐Guerrero et al. · Journal of Medicinal Chemistry · 1999 · 74 citations · Full text

Medicinal Chemistry, Biosynthesis, Biochemistry +13

Novel inhibitors of Trypanosoma cruzi dihydrofolate reductase

Fabio Zuccotto, Marketa Zvelebil, Reto Brun et al. · European Journal of Medicinal Chemistry · 2001 · 68 citations

Biochemistry, Parasitic Protozoa, Medicine +4

Application of a real-time PCR method for the detection of pine wood nematode, Bursaphelenchus xylophilus, in wood samples from lodgepole pine

Isabel Leal, Margaret Green, Eric Allen et al. · Nematology · 2007 · 63 citations

Pure Nematode Samples, Pathogen Detection, Molecular Biology +17

Acyclic Nucleoside Analogues as Inhibitors of<i>Plasmodium</i><i>f</i><i>alciparum</i>dUTPase

Corinne Nguyen, G.F. Ruda, Alessandro Schipani et al. · Journal of Medicinal Chemistry · 2006 · 57 citations · Full text