R.K. Perlman

Functional analysis of conserved residues in the active site of insulin-degrading enzyme.

R.K. Perlman, Barry D. Gehm, Wen-Lin Kuo et al. · Journal of Biological Chemistry · 1993 · 77 citations · Full text

Cellular Enzymology, Biochemistry, Conserved Residues +15

Conformational Changes in the α- and β-Subunits of the Insulin Receptor Identified by Anti-peptide Antibodies

R.K. Perlman, Donald P. Bottaro, Morris F. White et al. · Journal of Biological Chemistry · 1989 · 73 citations · Full text

Atp Binding Site, Immunology, Molecular Biology +21

Identification of zinc ligands of the insulin-degrading enzyme

R.K. Perlman, Marsha Rich Rosner · Journal of Biological Chemistry · 1994 · 59 citations · Full text

Chemical Biology, Insulin Signaling, Systems Biology +11

Mutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding.

Barry D. Gehm, Wen-Lin Kuo, R.K. Perlman et al. · Journal of Biological Chemistry · 1993 · 30 citations · Full text

Molecular Biology, Insulin Binding, Insulin Degradation +17

Insulin-Degrading Enzyme Does Not Require Peroxisomal Localization for Insulin Degradation*

Valérie Chesneau, R.K. Perlman, Wenlu Li et al. · Endocrinology · 1997 · 16 citations · Full text