Arumugam Balasubramanian

ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

Gang Du, Liam B. Healy, Liron David et al. · Nature · 2024 · 187 citations · Full text

Biochemistry, Natural Sciences, Mechanism Of Action +2

The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis

Arumugam Balasubramanian, Alan Y. Hsu, Laxman Ghimire et al. · Science Immunology · 2024 · 150 citations · Full text

Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis

Ivy Kekessie, Katarzyna Wegner, Isamir Martínez et al. · The Journal of Organic Chemistry · 2024 · 92 citations · Full text

Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution

Alan Y. Hsu, Qingxiang Huang, Xiong Pi et al. · Cell · 2025 · 52 citations

Inflammation, Complement System, Autoimmune Disease +5

Consecutive palmitoylation and phosphorylation orchestrates NLRP3 membrane trafficking and inflammasome activation

Li Nie, Chen-Jie Fei, Yizeng Fan et al. · Molecular Cell · 2024 · 47 citations

Proteinlipid Interaction, Signal Transduction, Inflammasome Activation +11