Liam B. Healy

ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D

Gang Du, Liam B. Healy, Liron David et al. · Nature · 2024 · 187 citations · Full text

Biochemistry, Natural Sciences, Mechanism Of Action +2

Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity

Pietro Fontana, Gang Du, Ying Zhang et al. · Cell · 2024 · 72 citations · Full text

S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity

Robbins Puthenveetil, Cheng Man Lun, R. Elliot Murphy et al. · Journal of Biological Chemistry · 2021 · 57 citations · Full text

Viral Replication, Viral Pathogenesis, Molecular Biology +18

ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation

Gang Du, Liam B. Healy, Liron David et al. · 2023 · 35 citations · Full text

Orthogonal Enzyme–Substrate Design Strategy for Discovery of Human Protein Palmitoyltransferase Substrates

Robbins Puthenveetil, Shelby A. Auger, Natalia Gómez‐Navarro et al. · Journal of the American Chemical Society · 2023 · 12 citations · Full text

Molecular Biotechnology, Protein Expression, Protein Function +13