Courtney J. Smith

Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits

Roshni Patel, Shaila Musharoff, Jeffrey P. Spence et al. · The American Journal of Human Genetics · 2022 · 76 citations · Full text

Allelic Variant, Genotype-phenotype Association, Medicine +9

Simple scaling laws control the genetic architectures of human complex traits

Yuval B. Simons, Hakhamanesh Mostafavi, Courtney J. Smith et al. · 2022 · 43 citations · Full text

Phenotypic Variation, Genetics, Genetic Architectures +26

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

Courtney J. Smith, Nasa Sinnott-Armstrong, Anna Cichońska et al. · eLife · 2022 · 41 citations · Full text

Lead Gwas Hits, Genetics, Metabolomic Profiling +19

Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases

Max Homilius, Wandi Zhu, Samuel S. Eddy et al. · Nature Genetics · 2023 · 36 citations · Full text

Correlation in Liability Among Relatives and Concordance in Twins

Courtney J. Smith · Human Heredity · 1972 · 16 citations

Family Medicine, Genetics, Genetic Epidemiology +19