Heather C. Losey

Structure of the UDP-Glucosyltransferase GtfB That Modifies the Heptapeptide Aglycone in the Biosynthesis of Vancomycin Group Antibiotics

A. M. Mulichak, Heather C. Losey, Christopher T. Walsh et al. · Structure · 2001 · 197 citations · Full text

Heptapeptide Aglycone, Biosynthesis, Biotransformation +11

Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA

Heather C. Losey, Alexander J. Ruthenburg, Gregory L. Verdine · Nature Structural & Molecular Biology · 2006 · 195 citations

Crystal Structure, Nucleic Acid Chemistry, Biochemistry +7

Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization

Cathryn A. Shaw-Reid, Neil L. Kelleher, Heather C. Losey et al. · Chemistry & Biology · 1999 · 166 citations · Full text

E. Coli Entf, Biosynthesis, Biochemistry +9

Tandem Action of Glycosyltransferases in the Maturation of Vancomycin and Teicoplanin Aglycones:  Novel Glycopeptides^,

Heather C. Losey, Mark W. Peczuh, Zhong Chen et al. · Biochemistry · 2001 · 158 citations

Glycobiology, Molecular Biology, Escherichia Coli +16

Incorporation of Glucose Analogs by GtfE and GtfD from the Vancomycin Biosynthetic Pathway to Generate Variant Glycopeptides

Heather C. Losey, Jiqing Jiang, John Biggins et al. · Chemistry & Biology · 2002 · 153 citations · Full text

Biosynthesis, Engineering, Biochemistry +10