The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation

Anne Månsson Kvarnhammar, Niina Veitonmäki, Karin Hägerbrand, +16

Journal for ImmunoTherapy of Cancer

CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation

Itziar Otano, Arantza Azpilikueta, Javier Glez‐Vaz, +19

Nature Communications

Intratumoral temozolomide synergizes with immunotherapy in a T cell-dependent fashion

Sara Fritzell, Emma Sandén, Sofia Eberstål, +3

Cancer Immunology Immunotherapy

Tumor ImmunologyIntratumoral TemozolomideAutoimmune DiseaseCancer ImmunosurveillanceMedicine +7

The effect of locally delivered cisplatin is dependent on an intact immune function in an experimental glioma model

Julio Enríquez Pérez, Sara Fritzell, Jan Kopecký, +3

Scientific Reports

Intratumoral COX‐2 inhibition enhances GM‐CSF immunotherapy against established mouse GL261 brain tumors

Sofia Eberstål, Emma Sandén, Sara Fritzell, +3

International Journal of Cancer

Neuro-oncologyProstaglandin E2Gm-csf ImmunotherapyCancer ImmunosurveillanceMedicine +12

Cure of established GL261 mouse gliomas after combined immunotherapy with GM‐CSF and IFNγ is mediated by both CD8⁺ and CD4⁺ T‐cells

Karin Enell Smith, Sara Fritzell, Wiaam Badn, +5

International Journal of Cancer

Cell TherapyImmunologyImmunologic MechanismIfngamma EffectImmunotherapeutics +18

IFNγ in combination with IL-7 enhances immunotherapy in two rat glioma models

Sara Fritzell, Sofia Eberstål, Emma Sandén, +3

Journal of Neuroimmunology

Cancer ImmunosurveillanceGliomaIl-7 Enhances ImmunotherapyImmunologyRat Glioma Models +5

Inhibition of cyclooxygenase-2 enhances immunotherapy against experimental brain tumors

Sofia Eberstål, Wiaam Badn, Sara Fritzell, +4

Cancer Immunology Immunotherapy

Neuro-oncologyCancer ImmunosurveillanceImmunologyAnti-cancer AgentCyclooxygenase-2 Enhances Immunotherapy +4

Immunizations With IFNγ Secreting Tumor Cells can Eliminate Fully Established and Invasive Rat Gliomas

Shorena Janelidze, Daniel Bexell, Wiaam Badn, +9

Journal of Immunotherapy