Paul J. Kling

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

B. Evans, Kenneth E. Rittle, Mark G. Bock et al. · Journal of Medicinal Chemistry · 1988 · 1.4K citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

In Vitro and in Vivo Evaluation of Dihydropyrimidinone C-5 Amides as Potent and Selective α_1A Receptor Antagonists for the Treatment of Benign Prostatic Hyperplasia

James C. Barrow, Philippe G. Nantermet, Harold G. Selnick et al. · Journal of Medicinal Chemistry · 2000 · 223 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Neuropeptide Y (NPY) binding sites in rat brain labeled with 125I-Bolton-Hunter NPY: Comparative potencies of various polypeptides on brain NPY binding and biological responses in the rat vas deferens

Raymond S.L. Chang, Victor J. Lotti, Tsing‐Bau Chen et al. · Life Sciences · 1985 · 114 citations

Life Sciences, Neuroscience, Pharmacology +15

Design and Synthesis of Novel α₁_a Adrenoceptor-Selective Antagonists. 1. Structure−Activity Relationship in Dihydropyrimidinones

Dhanapalan Nagarathnam, Shou Wu Miao, Bharat Lagu et al. · Journal of Medicinal Chemistry · 1999 · 113 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Analgesic activity of diflunisal [MK-647; 5-(2,4-difluorophenyl)salicylic acid] in rats with hyperalgesia induced by Freund's adjuvant.

C. A. Winter, Paul J. Kling, Dominick J. Tocco et al. · Journal of Pharmacology and Experimental Therapeutics · 1979 · 37 citations

Medicine, Medicinal Chemistry, Pharmacology +17